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 The
Human Genetic Analysis Resource (H.G.A.R.) is an NIH supported
resource that provides services and expertise in the form of collaborative
efforts and through the distribution of the Statistical Analysis
for Genetic Epidemiology (S.A.G.E. - Principle Investigator, Robert
C. Elston) software package. The Resource entertains requests for
collaboration from research workers who are collecting pedigree
data and wish to have their data analyzed by appropriate statistical
methods. The S.A.G.E. software provides the means to efficiently
analyze pedigree data in a variety of different ways. In addition,
short courses are provided that center primarily on theory and the
S.A.G.E. software package. The project is funded by the National Center
for Research Resources of the National Institutes of Health - U.S.
Public Health Service. Originally begun at Louisiana State University
Medical Center, the Resource has since moved to the Department of
Epidemiology and Biostatistics at Case Western Reserve University.
Center
for Health Promotion Research - The Center for Health Promotion
Research was founded in 2000 and is directed by Elaine A. Borawski,
Ph.D., Associate Professor of Epidemiology and Biostatistics. While
part of the Department of Epidemiology and Biostatistics in the CWRU
School of Medicine, the Center is located just off campus in The Triangle
office complex, providing easy access to the local community. The Center was created in response to an increasing interest in
community-based health promotion programs, evaluation and research
at CWRU. "The goal of the Center is to provide a common place
for faculty, community leaders, health educators, and students to
come together to share and develop ideas that will improve the health
of our community, with a particular focus on lifestyle changes",
states Dr. Borawski. The MISSION of the Center for Health Promotion Research is to develop,
evaluate, and disseminate health promotion and disease prevention
programs in diverse settings and populations, with an emphasis on
community-based research and evaluation. In addition, training and
education is a critical component of this mission, working to develop
behavioral scientists who specialize in health behavior and health
promotion and who understand the social and environmental context
in which healthy behaviors are developed and maintained.
 Tuberculosis
Research Unit - The National Institute of Allergy and Infectious
Diseases (NIAID), Division of Microbiology and Infectious Diseases
(DMID), established the Tuberculosis Research Unit (TBRU) through
a contract (N01-AI-95383) with Case Western University in 1994.
The purpose of this contract was to create a multidisciplinary,
international team dedicated to identifying and validating surrogate
markers of Mycobacterium tuberculosis (Mtb) infection and tuberculosis
(TB) disease progression, to identifying the correlates of the
human protective immune response to Mtb infection and to providing
a collaborative infrastructure for clinical research and early
stage clinical trials for drugs, vaccines and diagnostics for
TB. This contract was renewed for seven years in 1999.
The TBRU represents a cornerstone in
NIAID's contribution to the global fight against tuberculosis.
Since the resurgence of TB in the United States during the early
1990, NIAID has increased its funding for TB research from $3
million to $56 million in 2001, which helped establish a solid
research infrastructure for TB. The TBRU contract is designed
to support translation of basic research findings into tools
and approaches needed for the development of better drugs, vaccines
and diagnostic.
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