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SUDHA IYENGAR, PH.D.
Associate Professor
Division of Genetic and Molecular Epidemiology
Age-related macular degeneration
Age-related cataract
Fuchs' Dystrophy
Diabetic and non-diabetic nephropathy
Speech sound disorder
Office: Wolstein Research Building, 1300
Phone: (216) 368-4388
E-mail: ski@case.edu
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- Education
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Ph.D. 1992, MS 1988, University of Pittsburgh
- Research Interests
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Dr. Iyengar's laboratory is involved in finding human genes that cause complex diseases, both in young children, and in the general population as it ages. Although she has worked on many genetic diseases that affect worldwide populations, her current interest is on hereditary diseases that affect the eye, the kidney and the brain. Her laboratory's specific focus in on the following disorders: age-related macular degeneration, age-related cataract, Fuchs' dystrophy, diabetic and non-diabetic nephropathy, and speech sound disorder. Age-related macular degeneration, age-related cataracts and Fuchs' dystrophy are all common eye disorders that affect aging populations, and are among the leading causes of blindness in the world. Her group has identified genes for age-related macular degeneration and age-related cataracts and is working to do the same for Fuchs' dystrophy. Diabetic and non-diabetic nephropathy are caused when the body is unable to clear toxins and other substances due to malfunctioning kidneys. Kidney disease can occur by itself or can be a complication of another disease such as diabetes. It can be lethal as no long-term cure is available other than a transplant from a compatible donor, which means that the death rate for this set of diseases is very high. Dr. Iyengar is the Principal Investigator of the co-ordinating center for a large nationwide consortium called the Family Investigation of Nephropathy and Diabetes, which has just identified a major gene for non-diabetic nephropathy. Finally, communication disorders of speech, language and reading, profoundly affect young children. Dr. Iyengar's laboratory is in the process of identifying how changes in genes that play an important role in the brain cause these disorders in children. Identification of genes for these diseases will lead to important insights regarding how the patients can be better managed and how cures can be effected.
- Courses Taught
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EPBI
451: Principles of Genetic Epidemiology for Epidemiology and Biostatistics
- Publications
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Link To Publications
Last Updated: September 3, 2008
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