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case western reserve university

DEPT. OF EPIDEMIOLOGY
& BIOSTATISTICS

 

MARK D. SCHLUCHTER, PH.D.


Professor Division of Biostatistics

Associate Director for Biostatistics

Case Comprehensive Cancer Center



Office: School of Medicine, BRB Room G-19
Phone: (216) 368-2651
Fax: (216) 368-3970
E-mail: mds11@case.edu
Education
Ph.D. 1982, Biostatistics, University of California , Los Angeles

M.S. 1979, Biostatistics, University of California , Los Angeles

Research Interests
General design and analysis of clinical trials and epidemiologic studies; Methods for the analysis of longitudinal and incomplete data; Joint modeling of longitudinal and time-to-event data; Areas of focus: Cancer, Cystic Fibrosis, Pediatrics; HIV infection; Pulmonology


Honors
2002 Elected Fellow of the American Statistical Association
Courses Taught
EPBI 450: Clinical Trials and Intervention Studies
Professional Memberships

American Statistical Association
International Biometrics Society
Institute of Mathematical Statistics
Society for Clinical Trials
Society for Epidemiologic Research

Recent Publications

Schluchter MD , Greene T, Beck GJ. Analysis of change in the presence of informative censoring - application to a longitudinal clinical trial of progressive renal disease. Statistics in Medicine 2001; 20: 989-1007.

Kattan M, Platzker A, Mellins RB, Schluchter M , Chen XC, Colin A, Peavy H, Steinbach S, Wohl ME, and Hiatt P for the P 2 C 2 HIV Study Group. Respiratory diseases in the first year of life in children born to HIV infected mothers. Pediatr Pulmonol 2001; 31: 267-76.

Schluchter MD , Konstan MW, Davis PD. Jointly modeling the relationship between survival and pulmonary function in cystic fibrosis patients. Statistics in Medicine 2002; 21: 1271-1287.

Hack M, Flannery D, Klein N, Schluchter M , Cartar L, Borowski L. Young adult outcomes of very low birth weight babies. New England Journal of Medicine 2002: 346: 149-157.

Lipshultz SE, Easley KA, Orav EJ, Kaplan S, Starc TJ, Bricker JT, Lai WW, Moodie DS, Sopko G, Schluchter MD , Colan SD, for the P 2 C 2 HIV Study Group. Cardiovascular status of infants and children of HIV-infected women: The prospective P 2 C 2 HIV Study. The Lancet 2002; 360: 368-373.

Schluchter MD . Publication bias and heterogeneity in the relationship between systolic blood pressure, birth weight, and catch-up growth – a meta analysis. J. Hypertension 2003; 21: 273-279.

Zebracki, K., Drotar, D., Kirchner, H.L., Schluchter, M ., Redline, S., Kerscmar, C.M., Walders, N. Predicting attrition in a pediatric asthma intervention study. Journal of Pediatric Psychology 2003; 28, 519-528.

Hack M., Schluchter M , Cartar L, Rahman M, Cuttler L, Borawski E. Growth of very low birth weight infants to age 20 years. Pediatrics. 2003; 112: e30-8.

van Heeckeren AM, Scaria A, Schluchter MD , Ferkol, TW, Wadsworth S, Davis PB. Delivery of CFTR by adenoviral vector to cystic fibrosis mouse lung improves survival in a model of chronic Pseudomonas aeruginosa lung infection. Am J Physiol Lung Cell Mol Physiol 2004; 286: L717-726.

Hack M, Youngstrom E, Cartar L, Schluchter M , Taylor HG, Flannery D, Klein N, Borawski E. Behavioral outcomes and evidence of psychopathology among very low birth weight infants at age 20 years. Pediatrics 2004; 114: 932-940.

Davis PB, Schluchter MD , Konstan MW. Relation of sweat chloride concentration to severity of lung disease in cystic fibrosis. Pediatric Pulmonology 2004; 38: 204-209.

Li J, Schluchter MD . Conditional mixed models adjusting for nonignorable dropout with administrative censoring in longitudinal studies. Statistics in Medicine 2004; 22: 3489-3503.

Stoller JK, Tomashefski J, Crystal RG, Arroliga A, Strange C, Killian DN, Schluchter MD , Wiedemann HP. Mortality in individuals with severe deficiency of alpha 1-antitrypsin: Findings from the National Heart, Lung, and Blood Institute Registry. Chest 2005; 217: 1196-1204.

Hack M, Youngstrom EA, Cartar L, Schluchter M , Taylor HG, Flannery DJ, Klein N, Borawski E. Predictors of internalizing symptoms among very low birth weight young women. J Behavioral and Developmental Pediatrics 2005 26: 93-104.

Hart, MA, Konstan MW, Darrah RJ, Schluchter MD , Storfer-Isser A, Xue L, Drumm M. Beta 2 adrenergic receptor polymorphisms in cystic fibrosis. Pediatric Pulmonology 2005 39: 544-550.

Hack M, Taylor HG, Drotar D, Schluchter M , Cartar L, Wilson-Costello D, Klein N, Friedman H, Mercuri-Minich N, Morrow M. Poor predictive validity of the Bayley scales of infant development for cognitive function of extremely low birth weight children at school age. Pediatrics . 2005 116: 333-341.

Vonesh EF, Greene T, Schluchter M . Shared parameter models for the joint analysis of longitudinal data and event times. Statistics in Medicine 2006 25: 143-163.

Walders, N, Kercsmar C, Schluchter M , Drotar D, Redline S, Kirchner HL. An interdisciplinary intervention for under-treated pediatric asthma. Chest 2006 129: 292-299.

Hack M, Taylor HG, Drotar D, Schluchter M , Cartar L, Andreias L. Children of extremely low birth weight born in the 1990's: chronic conditions, functional limitations and special health care needs at school age. JAMA 2005 294: 318-325.

Drumm ML, Konstan MW, Schluchter MD , Handler A, Pace R, Zou F, Zariwala M, Fargo D, Xu A, Dunn, JM, Darrah RJ, Dorfman R, Sandford AJ, Corey C, Zielenski J, Durie P, Goddard K, Yankaskas JR, Wright FA, Knowles MR, for the Gene Modifier Study Group. Gene modifiers of lung disease in cystic fibrosis. New England Journal of Medicine , 2005 353: 1443-1453.

vanHeeckeren AM, Schluchter MD , Xue W, Davis PB. Response to acute lung infection with mucoid Pseudomonas aeruginosa in cystic fibrosis mice. American Journal of Respiratory and Critical Care Medicine. 2006 173: 288-296.

Drotar D, Hack M, Taylor HG, Schluchter M , Andreais L. The Impact of Extremely Low Birthweight on the Families of School-Age Children. Pediatrics 2006 117: 2006-2013.

Kercsmar CM, Dearborn DG, Schluchter M , Xue L, Kirchner HL, Sobelewski J, Greenberg SJ, Vesper SJ, Allan T. Reduction in asthma morbidity in children as a result of home remediation aimed at moisture sources. Environmental Health Perspectives 2006 (in press).

Schluchter MD , Konstan MW, Drumm ML, Yankaskas JR, Knowles MR. Classifying severity of cystic fibrosis lung disease using longitudinal pulmonary function data. American Journal of Respiratory and Critical Care Medicine 2006 (in press).



Last Updated: September 5, 2006